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Characterization of horizontal lipid bilayers as a model system to study lipid phase separation.

Abstract:

Artificial lipid membranes are widely used as a model system to study single ion channel activity using electrophysiological techniques. In this study, we characterize the properties of the artificial bilayer system with respect to its dynamics of lipid phase separation using single-molecule fluorescence fluctuation and electrophysiological techniques. We determined the rotational motions of fluorescently labeled lipids on the nanosecond timescale using confocal time-resolved anisotropy to pr...

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Publication status:
Published

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Publisher copy:
10.1016/j.bpj.2010.03.033

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
Role:
Author
Journal:
Biophysical journal
Volume:
98
Issue:
12
Pages:
2886-2894
Publication date:
2010-06-05
DOI:
EISSN:
1542-0086
ISSN:
0006-3495
URN:
uuid:2b8ea94f-82b5-4c9e-b0a7-d59ab6db0933
Source identifiers:
222197
Local pid:
pubs:222197

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