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Kinetics of viremia and NS1 antigenemia are shaped by immune status and virus serotype in adults with dengue.

Abstract:

BACKGROUND: Dengue is a major public health problem in tropical and subtropical countries. Exploring the relationships between virological features of infection with patient immune status and outcome may help to identify predictors of disease severity and enable rational therapeutic strategies. METHODS: Clinical features, antibody responses and virological markers were characterized in Vietnamese adults participating in a randomised controlled treatment trial of chloroquine. RESULTS: Of the ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Journal:
PLoS neglected tropical diseases
Volume:
5
Issue:
9
Pages:
e1309
Publication date:
2011-09-05
DOI:
EISSN:
1935-2735
ISSN:
1935-2727
URN:
uuid:2b8b30b8-50e5-42e4-8d2e-856993bb0db7
Source identifiers:
175213
Local pid:
pubs:175213

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