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Journal article

Imaging the cell surface and its organization down to the level of single molecules.

Abstract:

Determining the organization of key molecules on the surface of live cells in two dimensions and how this changes during biological processes, such as signalling, is a major challenge in cell biology and requires methods with nanoscale spatial resolution and high temporal resolution. Here, we review biophysical tools, based on scanning ion conductance microscopy and single-molecule fluorescence and the combination of both of these methods, which have recently been developed to address these i...

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Publication status:
Published

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Publisher copy:
10.1098/rstb.2012.0027

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
Role:
Author
Journal:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Volume:
368
Issue:
1611
Pages:
20120027
Publication date:
2013-02-05
DOI:
EISSN:
1471-2970
ISSN:
0962-8436
URN:
uuid:2b789aa8-6790-4682-b7a2-9028b564653b
Source identifiers:
377351
Local pid:
pubs:377351

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