- Abstract:
-
In Drosophila oocytes, dorso-anterior transport of gurken mRNA requires both the Dynein motor and the heterogeneous nuclear ribonucleoprotein (hnRNP) Squid. We show that gurken transcripts are transported directly on microtubules by Dynein in nonmembranous electron-dense transport particles that also contain Squid and the transport cofactors Egalitarian and Bicaudal-D. At its destination, gurken mRNA is statically anchored by Dynein within large electron-dense cytoplasmic structures known as ...
Expand abstract - Publication status:
- Published
- Journal:
- Developmental cell
- Volume:
- 13
- Issue:
- 4
- Pages:
- 523-538
- Publication date:
- 2007-10-05
- DOI:
- EISSN:
-
1878-1551
- ISSN:
-
1534-5807
- URN:
-
uuid:2b724bae-972d-4059-b914-4529af64dbe9
- Source identifiers:
-
100872
- Local pid:
- pubs:100872
- Copyright date:
- 2007
Journal article
Drosophila Squid/hnRNP helps Dynein switch from a gurken mRNA transport motor to an ultrastructural static anchor in sponge bodies.
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