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Thesis

Systematic overviews of the randomised evidence for the effects of traditional non-steroidal anti-inflammatory drugs and selective inhibitors of cyclo-oxygenase-2 on vascular and upper gastrointestinal outcomes

Abstract:

Background: Comparative assessments of the vascular and upper gastrointestinal risks of different regimens of non-steroidal anti-inflammatory drugs (NSAIDs) are required.

Methods: Meta-analyses were conducted, using individual participant data where possible, of placebo-controlled trials of a selective cyclo-oxygenase [COX]-2 inhibitor ('coxib') or traditional NSAID, or randomised trials of a coxib versus traditional NSAIDs. A prespecified subdivision of traditional N...

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Institution:
University of Oxford
Research group:
Clinical Trial Service Unit and Epidemiological Studies Unit
Oxford college:
St Cross College

Contributors

Role:
Supervisor
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Funding agency for:
Neeraj Bhala
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
URN:
uuid:2b6d8279-bce1-44bd-84c5-7658723786b2
Local pid:
ora:12085

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