Journal article icon

Journal article

A Burkholderia pseudomallei protein microarray reveals serodiagnostic and cross-reactive antigens.

Abstract:

Understanding the way in which the immune system responds to infection is central to the development of vaccines and many diagnostics. To provide insight into this area, we fabricated a protein microarray containing 1,205 Burkholderia pseudomallei proteins, probed it with 88 melioidosis patient sera, and identified 170 reactive antigens. This subset of antigens was printed on a smaller array and probed with a collection of 747 individual sera derived from 10 patient groups including melioidos...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1073/pnas.0812080106

Authors


Felgner, PL More by this author
Kayala, MA More by this author
Nakajima-Sasaki, R More by this author
Expand authors...
Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
106
Issue:
32
Pages:
13499-13504
Publication date:
2009-08-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:2b3902f0-3bdb-4997-a3f2-53a84b045e45
Source identifiers:
133496
Local pid:
pubs:133496

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP