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Thesis

Functional genomics of severe sepsis and septic shock

Abstract:

Sepsis is the systemic inflammatory response to an infection. Severe sepsis with multi organ failure is one of the commonest causes of admission to intensive care units, and is associated with poor early and late outcomes. The pathophysiology of sepsis is complex, and poorly understood. This is reflected in the limited and contentious treatment options for sepsis.

Genetic factors have been shown to be associated with the risk of and subsequent outcomes from infection. However, clear ...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Oxford college:
Christ Church
Role:
Author

Contributors

Division:
MSD
Department:
NDM
Role:
Supervisor
Division:
MSD
Department:
NDM
Role:
Supervisor
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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