- Abstract:
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Sepsis is the systemic inflammatory response to an infection. Severe sepsis with multi organ failure is one of the commonest causes of admission to intensive care units, and is associated with poor early and late outcomes. The pathophysiology of sepsis is complex, and poorly understood. This is reflected in the limited and contentious treatment options for sepsis.
Genetic factors have been shown to be associated with the risk of and subsequent outcomes from infection. However, clear ...
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- Publication date:
- 2013
- Type of award:
- DPhil
- Level of award:
- Doctoral
- URN:
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uuid:2b2afd65-82e0-4847-b7ae-960635b7e884
- Local pid:
- ora:7404
- Language:
- English
- Keywords:
- Subjects:
- Copyright holder:
- Jayachandran Radhakrishnan
- Copyright date:
- 2012
Thesis
Functional genomics of severe sepsis and septic shock
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