Intra-patient variability in tacrolimus exposure - a useful tool for clinical practice?
- The narrow therapeutic window for calcineurin inhibitors (CNI) remains a challenge in the management of transplant recipients, with under-exposure risking acute rejection and over-exposure resulting in acute and chronic impairment of graft function. Optimisation of CNI exposure by computerised dosing and different monitoring strategies have long been an area of interest in the transplant literature (1,2).
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- Peer reviewed
(Accepted manuscript, pdf, 93.5KB)
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- Steunstichting ESOT
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- Copyright © 2016 Steunstichting ESOT. This is the accepted manuscript version of the article. The final version is available online from Wiley at: https://doi.org/10.1111/tri.12806
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