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The influence of ApoE4 on clinical progression of dementia: a meta-analysis.

Abstract:

OBJECTIVE: ApoE4 is a risk factor for the development of Alzheimer's disease, and has a functional role suggesting its importance in the neuropathology of dementia. We present a meta-analysis to investigate whether ApoE4 also affects the clinical progression of dementia in terms of cognitive decline or mortality. METHODS: We searched Medline, Embase and PsychINFO from 1990 until April 2009, for case control or cohort studies which investigated the effect of ApoE4 on progression of dementia. ...

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Publication status:
Published

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Publisher copy:
10.1002/gps.2559

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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Journal:
International journal of geriatric psychiatry
Volume:
26
Issue:
5
Pages:
520-526
Publication date:
2011-05-05
DOI:
EISSN:
1099-1166
ISSN:
0885-6230
URN:
uuid:2afdf843-f5ac-4955-948d-087eb6bad605
Source identifiers:
139250
Local pid:
pubs:139250

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