Cognitive activation in conjunction with pharmacological challenge was used to demonstrate neuromodulation in man. Using positron emission tomography (PET), measurements of regional cerebral blood flow were made during the performance of memory tasks, before and after the administration of apomorphine (dopamine agonist), buspirone (5-HT1A partial agonist) or placebo. Drug effects on memory-induced increases in regional cerebral blood flow were assessed, on a voxel-by-voxel basis, using statis...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Measuring the neuromodulatory effects of drugs in man with positron emission tomography.
Views and Downloads
If you are the owner of this record, you can report an update to it here: Report update to this record