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Rapid detection of Burkholderia pseudomallei in blood cultures using a monoclonal antibody-based immunofluorescent assay.

Abstract:

Melioidosis is a severe bacterial infection caused by Burkholderia pseudomallei. Rapid antimicrobial therapy is necessary to improve patient outcome, which is aided by direct detection of B. pseudomallei in clinical samples. A drawback for all antigen assays is that the number of B. pseudomallei in blood usually falls below the achievable level of detection. We performed a prospective cohort study of 461 patients with 541 blood cultures to evaluate the utility of a pre-incubation step prior t...

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Publication status:
Published

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Publisher copy:
10.4269/ajtmh.13-0212

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Tandhavanant, S More by this author
Wongsuvan, G More by this author
Wuthiekanun, V More by this author
Teerawattanasook, N More by this author
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Journal:
The American journal of tropical medicine and hygiene
Volume:
89
Issue:
5
Pages:
971-972
Publication date:
2013-11-05
DOI:
EISSN:
1476-1645
ISSN:
0002-9637
URN:
uuid:2adf24ef-3271-42b5-b94a-22cd21c296f9
Source identifiers:
429278
Local pid:
pubs:429278

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