Journal article icon

Journal article

Bod1 regulates protein phosphatase 2A at mitotic kinetochores

Abstract:

Mitotic entry and progression require the activation of several mitotic kinases and the proper regulation and localization of several phosphatases. The activity and localization of each of these enzymes is tightly controlled through a series of specific activators, inhibitors and regulatory subunits. Two proteins, Ensa and Arpp-19, were recently identified as specific inhibitors of PP2A-B55 and are critical for allowing full activity of Cdk1/cyclin B and entry into mitosis. Here we show that ...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1038/ncomms3677

Authors


Porter, IM More by this author
More by this author
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Swedlow, JR More by this author
Publisher:
Nature Publishing Publisher's website
Journal:
Nature Communications Journal website
Volume:
4
Pages:
Article 2677
Publication date:
2013-10-25
Acceptance date:
2013-09-26
DOI:
ISSN:
2041-1723
Pubs id:
pubs:680671
URN:
uri:2adcc4cf-1330-460b-a8e2-8443e4b5da93
UUID:
uuid:2adcc4cf-1330-460b-a8e2-8443e4b5da93
Local pid:
pubs:680671

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP