Journal article
Post-conditioning with lipopolysaccharide reduces the inflammatory infiltrate to the injured brain and spinal cord: a potential neuroprotective treatment.
- Abstract:
-
Systemic infection often accompanies or precedes acute brain injury, but it remains unclear how the systemic response contributes to outcome. To examine this problem we have microinjected recombinant interleukin-1beta (IL-1beta), a cytokine associated with acute brain injury, into the rat brain parenchyma and either preceded or followed this challenge with the intravenous injection of lipopolysaccharide (LPS), which mimics systemic inflammatory response syndrome. The microinjection of IL-1bet...
Expand abstract
- Publication status:
- Published
Actions
Authors
Bibliographic Details
- Journal:
- European journal of neuroscience
- Volume:
- 22
- Issue:
- 10
- Pages:
- 2441-2450
- Publication date:
- 2005-11-01
- DOI:
- EISSN:
-
1460-9568
- ISSN:
-
0953-816X
- Source identifiers:
-
185226
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:185226
- UUID:
-
uuid:2a7cdaa7-1319-4641-9814-fc041eb4f078
- Local pid:
- pubs:185226
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2005
If you are the owner of this record, you can report an update to it here: Report update to this record