Journal article icon

Journal article

Is placebo response in antidepressant trials rising or not? A reanalysis of datasets to conclude this long-lasting controversy.

Abstract:

It had long been believed that placebo response rates in antidepressant trials have been increasing and that they were responsible for rising numbers of so-called failed antidepressant trials. Two recent systematic reviews examined this issue and reached completely opposite findings. Furukawa and colleagues in a paper published in 2016 found that the placebo response rates are stable since 1991 and the apparent increase up to 2000 was confounded by changes in trial design features. By contras...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

Actions


Access Document


Files:
Publisher copy:
10.1136/eb-2017-102827

Authors


More by this author
ORCID:
0000-0003-2159-3776
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Psychiatry
ORCID:
0000-0001-5179-8321
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Psychiatry
Expand authors...
Publisher:
BMJ Publishing Group Publisher's website
Journal:
Evidence-Based Mental Health Journal website
Volume:
21
Issue:
1
Pages:
1-3
Publication date:
2018-01-05
Acceptance date:
2017-12-15
DOI:
EISSN:
1468-960X
ISSN:
1362-0347
Pubs id:
pubs:821448
URN:
uri:2a755eeb-1703-4017-87cc-52a06f407704
UUID:
uuid:2a755eeb-1703-4017-87cc-52a06f407704
Local pid:
pubs:821448
Language:
English
Keywords:

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP