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Journal article

Fluorescence fluctuation spectroscopy in reduced detection volumes.

Abstract:

Fluorescence fluctuation spectroscopy is a versatile technique applied to in vitro and in vivo investigations of biochemical processes such as interactions, mobilities or densities with high specifity and sensitivity. The prerequisite of this dynamical fluorescence technique is to have, at a time, only few fluorescent molecules in the detection volume in order to generate significant fluorescence fluctuations. For usual confocal fluorescence microscopy this amounts to a useful concentration i...

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Publication status:
Published

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Publisher copy:
10.2174/138920106775789629

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
Role:
Author
Journal:
Current pharmaceutical biotechnology
Volume:
7
Issue:
1
Pages:
51-66
Publication date:
2006-02-05
DOI:
EISSN:
1873-4316
ISSN:
1389-2010
URN:
uuid:2a26439d-5eae-4b01-8f1b-0f42ed476993
Source identifiers:
222164
Local pid:
pubs:222164

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