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Accelerated evolution of Protocadherin11X/Y: a candidate gene-pair for cerebral asymmetry and language.

Abstract:

It has been argued that cerebral asymmetry (the "torque") is the characteristic that defines the human brain and that morphological findings in psychosis are consistent with a deviation in this sex-dependent dimension of brain growth. Evidence from sex chromosome aneuploidies and an association within families between sex and handedness is consistent with the presence of a determinant of cerebral asymmetry (a possible correlate of language) on the X and the Y chromosomes. During hominid evolu...

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Publisher copy:
10.1002/ajmg.b.30357

Authors


Williams, NA More by this author
Giouzeli, M More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Journal:
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
Volume:
141B
Issue:
6
Pages:
623-633
Publication date:
2006-09-05
DOI:
EISSN:
1552-485X
ISSN:
1552-4841
URN:
uuid:2a2024b8-a67d-48c6-91d7-8208f10f254a
Source identifiers:
470825
Local pid:
pubs:470825

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