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The isolation of cDNAs from OATL1 at Xp 11.2 using a 480-kb YAC.

Abstract:

Using an ornithine-delta-aminotransferase (OAT) cDNA, we identified five YACs that cover two nonadjacent OAT-related loci in Xp11.2-p11.3, designated OATL1 (distal) and OATL2 (proximal). Because several retinal degenerative disorders map to this region, we used YAC2 (480 kb), which covers the most distal part of OATL1, as a probe to screen a retinal cDNA library. From 8 x 10(4) plaques screened, we isolated 13 clones. Two were OAT cDNAs. The remaining 11 were divided into eight groups by cros...

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Publication status:
Published

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Publisher copy:
10.1006/geno.1993.1208

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Journal:
Genomics More from this journal
Volume:
16
Issue:
2
Pages:
440-446
Publication date:
1993-05-01
DOI:
EISSN:
1089-8646
ISSN:
0888-7543
Language:
English
Keywords:
Pubs id:
pubs:44091
UUID:
uuid:2a0bfc7d-397a-4507-872a-33cdcef0a0e2
Local pid:
pubs:44091
Source identifiers:
44091
Deposit date:
2012-12-19

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