Journal article icon

Journal article

Tolerance induction to human stem cell transplants with extension to their differentiated progeny.

Abstract:

There is increasing interest in transplantation of human stem cells for therapeutic purposes. It would benefit future application if one could achieve their long-term acceptance and functional differentiation in allogeneic hosts using minimal immunosuppression. Allogeneic stem cell transplants differ from conventional tissue transplants insofar as not all alloantigens are revealed during tolerance induction. This risks that the immune system tolerized to antigens expressed by progenitors may ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/ncomms6629

Authors


Expand authors...
Journal:
Nature communications
Volume:
5
Pages:
5629
Publication date:
2014
DOI:
EISSN:
2041-1723
ISSN:
2041-1723
URN:
uuid:2a095974-48cf-45d0-9e47-f9185febd046
Source identifiers:
493170
Local pid:
pubs:493170
Language:
English

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP