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Journal article

TCR beta polymorphisms and multiple sclerosis.

Abstract:

A total of 267 families with two or more siblings with multiple sclerosis (MS) were genotyped with 14 restriction fragment length polymorphisms at the TCR beta locus. A nonparametric linkage analysis of the data showed no evidence for linkage to this locus (mlod=0.11). No significant allelic or haplotype transmissions were observed in the total sample of 565 patients. After stratification for the presence of HLA DRB1*15, an association was observed between the BV25S1*1-BV26S1*1-BV2S1*1 haplot...

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Publication status:
Published

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Publisher copy:
10.1038/sj.gene.6364091

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Author
Journal:
Genes and immunity More from this journal
Volume:
5
Issue:
5
Pages:
337-342
Publication date:
2004-08-01
DOI:
EISSN:
1476-5470
ISSN:
1466-4879
Language:
English
Keywords:
Pubs id:
pubs:32731
UUID:
uuid:2a02770f-5325-4147-a528-4b9f1dbf9853
Local pid:
pubs:32731
Source identifiers:
32731
Deposit date:
2012-12-19

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