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Diverse odor-conditioned memories require uniquely timed dorsal paired medial neuron output.

Abstract:

Amnesiac mutant flies have an olfactory memory defect. The amn gene encodes a homolog of vertebrate pituitary adenylate cyclase-activating peptide (PACAP), and it is strongly expressed in dorsal paired medial (DPM) neurons. DPM neurons ramify throughout the mushroom bodies in the adult fly brain, and they are required for stable memory. Here, we show that DPM neuron output is only required during the consolidation phase for middle-term odor memory and is dispensable during acquisition and rec...

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Authors


Stratmann, M More by this author
Perrat, PN More by this author
Vosshall, LB More by this author
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Journal:
Neuron
Volume:
44
Issue:
3
Pages:
521-533
Publication date:
2004-10-05
DOI:
EISSN:
1097-4199
ISSN:
0896-6273
URN:
uuid:29f4bc20-206b-4ed3-b3ab-06e833517b6b
Source identifiers:
252416
Local pid:
pubs:252416

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