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Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom.

Abstract:

Variation in CAPN10, the gene encoding the ubiquitously expressed cysteine protease calpain-10, has been associated with type 2 diabetes in Mexican Americans and in two northern-European populations, from Finland and Germany. We have studied CAPN10 in white subjects of British/Irish ancestry, using both family-based and case-control studies. In 743 sib pairs, there was no evidence of linkage at the CAPN10 locus, which thereby excluded it as a diabetes-susceptibility gene, with an overall sib ...

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Publication status:
Published

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Publisher copy:
10.1086/323315

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Journal:
American journal of human genetics More from this journal
Volume:
69
Issue:
3
Pages:
544-552
Publication date:
2001-09-01
DOI:
EISSN:
1537-6605
ISSN:
0002-9297
Language:
English
Keywords:
Pubs id:
pubs:27690
UUID:
uuid:29e71b2e-9bbe-4413-81ba-46a6cb6e70d7
Local pid:
pubs:27690
Source identifiers:
27690
Deposit date:
2012-12-19

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