BACKGROUND: Despite the inevitability of disease progression in amyotrophic lateral sclerosis, there is a high degree of prognostic heterogeneity in all subtypes. Some bulbar-onset (BO) patients may develop rapid anarthria yet remain ambulant for a prolonged period, whereas others progress rapidly, with early generalisation of motor weakness to the limbs and respiratory muscles. Diagnostic delay is a common occurrence in ALS, and many BO patients report having attended other specialist clinic...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
The diagnostic pathway and prognosis in bulbar-onset amyotrophic lateral sclerosis.
If you are the owner of this record, you can report an update to it here: Report update to this record