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Journal article

The diagnostic pathway and prognosis in bulbar-onset amyotrophic lateral sclerosis.

Abstract:

BACKGROUND: Despite the inevitability of disease progression in amyotrophic lateral sclerosis, there is a high degree of prognostic heterogeneity in all subtypes. Some bulbar-onset (BO) patients may develop rapid anarthria yet remain ambulant for a prolonged period, whereas others progress rapidly, with early generalisation of motor weakness to the limbs and respiratory muscles. Diagnostic delay is a common occurrence in ALS, and many BO patients report having attended other specialist clinic...

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Publication status:
Published

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Publisher copy:
10.1016/j.jns.2010.03.028

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Goodfellow, JA More by this author
Marsden, R More by this author
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Journal:
Journal of the neurological sciences
Volume:
294
Issue:
1-2
Pages:
81-85
Publication date:
2010-07-05
DOI:
EISSN:
1878-5883
ISSN:
0022-510X
URN:
uuid:29b72f41-9a5b-405e-a9e3-d0d5aef65b12
Source identifiers:
245046
Local pid:
pubs:245046

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