Considerable evidence indicates a link between systemic inflammation and central 5-HT function. This study used pharmacological magnetic resonance imaging (phMRI) to study the effects of systemic inflammatory events on central 5-HT function. Changes in blood oxygenation level dependent (BOLD) contrast were detected in selected brain regions of anaesthetised rats in response to intravenous administration of the 5-HT-releasing agent, fenfluramine (10 mg/kg). Further groups of rats were pre-trea...Expand abstract
- Publication date:
- Source identifiers:
- Local pid:
- Copyright date:
Systemic inflammation alters central 5-HT function as determined by pharmacological MRI.
If you are the owner of this record, you can report an update to it here: Report update to this record