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Interleukin-23 and TH17 cells in transplantation immunity: does 23+17 equal rejection?

Abstract:
Interleukin-23 (IL-23) and the recently discovered Th17 cells have been implicated in the pathogenesis of autoimmune diseases. This review will discuss current understanding of T-cell subsets in transplantation immunity and will explore the role of IL-23 and Th17 cells in allograft rejection, tolerance, and ischemia reperfusion injury.
Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Journal:
Transplantation
Volume:
84
Issue:
9
Pages:
1071-1074
Publication date:
2007-11-05
DOI:
EISSN:
1534-6080
ISSN:
0041-1337
URN:
uuid:2997713c-2135-4b37-b71d-7fad2fdef923
Source identifiers:
135974
Local pid:
pubs:135974

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