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Expression of vascular endothelial growth factor (VEGF) and its receptors in thyroid carcinomas of follicular origin: a potential autocrine loop.

Abstract:

OBJECTIVE: The aim of this study was to clarify the role of vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) pathways in thyroid tumourigenesis. METHODS: We examined VEGF, VEGFR-1 and VEGFR-2 expression on 34 papillary thyroid carcinomas (PTCs), 18 follicular thyroid carcinomas (FTCs), eight poorly differentiated thyroid carcinomas (PDTCs) and on a thyroid tumour-derived cell line (NPA'87) by immunohistochemistry, reverse transcriptase PCR, immunofluorescence and Western b...

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Publisher copy:
10.1530/eje.1.02009

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Journal:
European journal of endocrinology / European Federation of Endocrine Societies
Volume:
153
Issue:
5
Pages:
701-709
Publication date:
2005-11-05
DOI:
EISSN:
1479-683X
ISSN:
0804-4643
URN:
uuid:292fc600-8797-436d-8b87-8d81bb02d03f
Source identifiers:
428947
Local pid:
pubs:428947

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