Safety and efficacy of iron therapy on reducing red blood cell transfusion requirements and treating anaemia in critically ill adults: A systematic review with meta-analysis and trial sequential analysis
Purpose To evaluate the safety (risk of infection) and efficacy (transfusion requirements, changes in haemoglobin (Hb)) of iron therapy in adult intensive care unit (ICU) patients.
Materials and methods We systematically searched seven databases for all relevant studies until January 2018 and included randomized (RCT) studies comparing iron, by any route, with placebo/no iron.
Results 805 participants from 6 RCTs were in... Expand abstract
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- Peer review status:
- Peer reviewed
- Publisher copy:
- Elsevier Publisher's website
- Journal of Critical Care Journal website
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- Copyright holder:
- Elsevier Inc.
- Copyright date:
- © 2018 Elsevier Inc. All rights reserved.
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