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Journal article

The length of a tetranucleotide repeat tract in Haemophilus influenzae determines the phase variation rate of a gene with homology to type III DNA methyltransferases.

Abstract:

Haemophilus influenzae is an obligate commensal of the upper respiratory tract of humans that uses simple repeats (microsatellites) to alter gene expression. The mod gene of H. influenzae strain Rd has homology to DNA methyltransferases of type III restriction/modification systems and has 40 tetranucleotide (5'-AGTC) repeats within its open reading frame. This gene was found in 21 out of 23 genetically distinct H. influenzae strains, and in 13 of these strains the locus contained repeats. H. ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
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Journal:
Molecular microbiology
Volume:
35
Issue:
1
Pages:
211-222
Publication date:
2000-01-05
DOI:
EISSN:
1365-2958
ISSN:
0950-382X
URN:
uuid:2916948e-04b1-4847-90af-0b215f63166a
Source identifiers:
9958
Local pid:
pubs:9958

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