Directed differentiation of dendritic cells from mouse embryonic stem cells: a novel tool for identifying targets for immunotherapy

Conference item

Abstract:: Dendritic cells (DC) form a diverse system of antigen presenting cells (APC) responsible for orchestrating the body's response to infection. As the only cell type capable of eliciting effector functions among antigen-naive T cells, DC act at the very heart of the immune response, either driving immunity or securing a state of self-tolerance. Although DC hold promise as targets for immune intervention, the mechanisms responsible for defining the balance between these opposing forces currently ...
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Journal:: PLURIPOTENT STEM CELLS: THERAPEUTIC PERSPECTIVES AND ETHICAL ISSUES More from this journal
Pages:: 25-38
Publication date:: 2001-01-01
Event title:: International Workshop on Pluripotent Stem Cells - Therapeutic Perspectives and Ethical Issues
ISBN:: 274200369X

Keywords:: ANTIGEN PRESENTATION

HUMAN BLASTOCYSTS

ES CELLS

ANTITUMOR IMMUNITY

apoptotic cells

INDUCTION

T-CELLS

IN-VIVO

CLASS-II COMPLEXES

ACQUIRED THYMIC TOLERANCE
Pubs id:: pubs:30174
UUID:: uuid:290cdaaa-f4bf-4b55-bbd8-51457669388f
Local pid:: pubs:30174
Source identifiers:: 30174
Deposit date:: 2012-12-19

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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