- Abstract:
-
We have used proteomic fingerprinting to investigate diagnosis of Alzheimer's disease (AD). Samples of lumbar cerebrospinal fluid (CSF) from clinically-diagnosed AD cases (n = 33), age-matched controls (n = 20), and mild cognitive impairment (MCI) patients (n = 10) were used to obtain proteomic profiles, followed by bioinformatic analysis that generated a set of potential biomarkers in CSF samples that could discriminate AD cases from controls. The identity of the biomarker ions was determine...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.3233/jad-2011-111505
-
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- Journal:
- Journal of Alzheimer's disease : JAD
- Volume:
- 28
- Issue:
- 3
- Pages:
- 625-636
- Publication date:
- 2012
- DOI:
- EISSN:
-
1875-8908
- ISSN:
-
1387-2877
- URN:
-
uuid:28d40780-f937-42de-8c5b-43b5a057cfe7
- Source identifiers:
-
317160
- Local pid:
- pubs:317160
- Language:
- English
- Keywords:
- Copyright date:
- 2012
Journal article
Identification of SPARC-like 1 protein as part of a biomarker panel for Alzheimer's disease in cerebrospinal fluid.
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