- A stereocontrolled synthesis of norphenyl hyperolactone C together with its utility as a direct precursor to the anti-HIV agent hyperolactone C and analogues by addition of organolithiums, are described. Preliminary studies to access this key building block in a catalytic enantioselective manner are also reported.
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An approach to hyperolactone C and analogues using late stage conjugate addition on an oxonium ylide-derived spirofuranone.
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