- Abstract:
-
The ability of immune complexes derived from patients with type II mixed essential cryoglobulinemia to trigger the production of interleukin 1 (IL 1) was investigated. Immune complexes containing either IgM/IgG or IgA/IgG aggregates were shown to induce IL 1 production in human peripheral blood monocyte-enriched populations. Interferon-gamma alone did not induce detectable IL 1, but increased the IL 1 production induced by the immune complexes. Tumor necrosis factor-alpha, which is a potent i...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/eji.1830190130
-
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- Journal:
- European journal of immunology
- Volume:
- 19
- Issue:
- 1
- Pages:
- 189-192
- Publication date:
- 1989-01-05
- DOI:
- EISSN:
-
1521-4141
- ISSN:
-
0014-2980
- URN:
-
uuid:28c8ac91-ef3b-4bf0-ad18-c41d904ce050
- Source identifiers:
-
481777
- Local pid:
- pubs:481777
- Copyright date:
- 1989
Journal article
Mechanism of immune complex-mediated damage: induction of interleukin 1 by immune complexes and synergy with interferon-gamma and tumor necrosis factor-alpha.
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