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Journal article

Human alpha beta T-cell receptor CD4-CD8 T-cell clones are predominantly Th0-like.

Abstract:

The cytokine production profile, focusing on interleukin-4 (IL-4), interferon-gamma (IFN-gamma) and interleukin-10 (IL-10) of human CD4+, CD8+ and CD4- CD8- alpha beta T cells cloned from the peripheral blood of healthy individuals was compared. Solid-phase anti-CD3 stimulation of CD4- CD8- alpha beta T cell clones from one individual revealed a significantly increased frequency of IL-4-producing clones (81%), compared to CD4+ T cells (24%) or CD8+ (28%). All five CD4- CD8- alpha beta T-cell ...

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Publication status:
Published

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Authors


Katsikis, PD More by this author
Murison, JG More by this author
Hibbart, LM More by this author
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Journal:
Immunology
Volume:
84
Issue:
4
Pages:
501-504
Publication date:
1995-04-05
EISSN:
1365-2567
ISSN:
0019-2805
URN:
uuid:28a16866-b9af-4bca-bf81-18df519ee8bf
Source identifiers:
481643
Local pid:
pubs:481643

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