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Solid phase peptide templated glycosidic bond formation

Abstract:

Glycosylation reactions performed between a glycosyl donor and acceptor covalently linked to a peptide template both in the solution and solid phase give similar yields and product distributions. The adoption of a solid phase approach opens the way for the synthesis of libraries of peptide templates in an attempt to screen for particular peptide sequences that effect complete regio-and stereochemical control during glycosidic bond formation, whilst the use of second generation donors allows t...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
TETRAHEDRON-ASYMMETRY More from this journal
Volume:
14
Issue:
9
Pages:
1201-1210
Publication date:
2003-05-02
DOI:
ISSN:
0957-4166
Language:
English
Pubs id:
pubs:38676
UUID:
uuid:2890fa4e-af0e-4547-8643-b72d856f1ef4
Local pid:
pubs:38676
Source identifiers:
38676
Deposit date:
2012-12-19

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