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The somatotropic axis in short children born small for gestational age: relation to insulin resistance.

Abstract:

To determine whether hyperinsulinemia and reduced insulin sensitivity in individuals born small for gestational age (SGA) could be related to persisting abnormalities of the GH/IGF-I axis, we assessed overnight GH secretory profiles and measured fasting glucose, insulin, intact and 32,33 split proinsulin, and IGF-I levels in 16 short SGA children (age range 2.3-8.0 y) and in controls. Insulin sensitivity was calculated using the homeostasis model. Compared with short normal-birthweight contro...

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Publication status:
Published

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Journal:
Pediatric research More from this journal
Volume:
51
Issue:
1
Pages:
76-80
Publication date:
2002-01-01
DOI:
EISSN:
1530-0447
ISSN:
0031-3998
Language:
English
Keywords:
Pubs id:
pubs:184716
UUID:
uuid:28901417-4a45-46a8-9f11-8a053052bb39
Local pid:
pubs:184716
Source identifiers:
184716
Deposit date:
2012-12-19

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