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Journal article

A high-throughput induction gene trap approach defines C4ST as a target of BMP signaling.

Abstract:

Here we describe a novel gene trap protocol to screen for target genes that are regulated during inductive events in undifferentiated and differentiated mouse embryonic stem cells. This approach integrates several features that allows in vitro screening of large numbers of gene trap clones prior to generating lines of mutant mice. Moreover, targets of spatially and temporally restricted signaling pathways can be analyzed by screening undifferentiated ES cells versus ES cells differentiated in...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Role:
Author
Journal:
Mechanisms of development
Volume:
118
Issue:
1-2
Pages:
77-89
Publication date:
2002-10-05
DOI:
EISSN:
1872-6356
ISSN:
0925-4773
URN:
uuid:287803f5-c0fb-4b9e-ac43-d1fa35f8a546
Source identifiers:
130868
Local pid:
pubs:130868

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