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Nitric oxide modulates the release of vasopressin from rat hypothalamic explants.

Abstract:

The enzyme nitric oxide (NO) synthase is present in the paraventricular nucleus, while nitric oxide has recently been shown to inhibit the stimulated release of corticotrophin-releasing hormone (CRH) in vitro. Thus the possible role of NO in regulating, vasopressin (AVP), which also plays an important role in pituitary-adrenal activity, has been investigated. The effects were studied of the NO donors, L-arginine, syndnonimine-1 (SIN-1) and sodium nitroprusside, on both the basal and stimulate...

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Publication status:
Published

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Publisher copy:
10.1210/en.133.3.1466

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Journal:
Endocrinology
Volume:
133
Issue:
3
Pages:
1466-1469
Publication date:
1993-09-05
DOI:
EISSN:
1945-7170
ISSN:
0013-7227
URN:
uuid:28764e99-8215-4df3-a746-46a0a85fabc7
Source identifiers:
138459
Local pid:
pubs:138459

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