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Young women partition fatty acids towards ketone body production rather than VLDL-TAG synthesis, compared with young men.

Abstract:

Before the menopause, women are relatively protected against CVD compared with men. The reasons for this sex difference are not completely understood, but hepatic fatty acid metabolism may play a role. The present study aimed to investigate the utilisation of plasma NEFA by the liver and to determine whether they are partitioned differently into ketone bodies and VLDL-TAG in healthy, lean young men and women. Volunteers were studied during a prolonged overnight fast (12-19 h) using an intrave...

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Publication status:
Published

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Publisher copy:
10.1017/s0007114510004472

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM, Biomedical Research Centre
Role:
Author
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Journal:
The British journal of nutrition
Volume:
105
Issue:
6
Pages:
857-865
Publication date:
2011-03-05
DOI:
EISSN:
1475-2662
ISSN:
0007-1145
URN:
uuid:286e965e-d4b8-4bed-b53d-dbe06a0272f2
Source identifiers:
115690
Local pid:
pubs:115690

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