- Abstract:
-
The engraftment potential of myeloproliferative neoplasms in immunodeficient mice is low. We hypothesized that the physiological expression of human cytokines (macrophage colony-stimulating factor, interleukin-3, granulocyte-macrophage colony-stimulating factor, and thrombopoietin) combined with human signal regulatory protein α expression in Rag2−/−Il2rγ−/− (MISTRG) mice might provide a supportive microenvironment for the development and maintenance of hematopoietic stem and progenitor cells...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Publisher:
- American Society of Hematology Publisher's website
- Journal:
- Blood Advances Journal website
- Volume:
- 4
- Issue:
- 11
- Pages:
- 2477-2488
- Publication date:
- 2020-06-05
- Acceptance date:
- 2020-04-28
- DOI:
- EISSN:
-
2473-9537
- ISSN:
-
2473-9529
- Pmid:
-
32502268
- Pubs id:
-
1111236
- Local pid:
- pubs:1111236
- Language:
- English
- Keywords:
- Format:
- Copyright holder:
- American Society of Hematology
- Copyright date:
- 2020
- Rights statement:
- © 2020 by The American Society of Hematology
Journal article
Enhanced engraftment of human myelofibrosis stem and progenitor cells in MISTRG mice
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