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Journal article

Role of a defunctioning stoma in the management of large bowel Crohn's disease.

Abstract:

BACKGROUND: The faecal stream plays a significant role in the pathogenesis of Crohn's disease. This retrospective study aimed to assess the effect of faecal diversion on the natural history of refractory Crohn's colitis (RCC) and severe perianal disease (PAD). METHODS: All patients undergoing a defunctioning stoma without resection for RCC or PAD between 1970 and 1997 were studied. Indications for surgery, acute clinical response, subsequent outcome and stoma rates were recorded. RESULTS: Som...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, NDM, NDM Experimental Medicine
Role:
Author
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Journal:
The British journal of surgery
Volume:
87
Issue:
8
Pages:
1063-1066
Publication date:
2000-08-05
DOI:
EISSN:
1365-2168
ISSN:
0007-1323
URN:
uuid:283262da-8220-4c55-a6e7-befef501e082
Source identifiers:
21184
Local pid:
pubs:21184

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