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Genetic polymorphisms of platelet glycoprotein Ia and the risk for premature myocardial infarction: effects on the release of sCD40L during the acute phase of premature myocardial infarction.

Abstract:

OBJECTIVES: The aim of this research was to evaluate the effect of genetic polymorphisms C807T and G1648A of platelet glycoprotein Ia (GPIa), on the risk for myocardial infarction (MI) and on the release of soluble CD40 ligand (sCD40L) during the acute phase of MI and one year after the event. BACKGROUND: C807T and G1648A polymorphisms affect the density of GPIa on platelet surface, but their effect on the risk for MI and the release of sCD40L is unknown. METHODS: The study population consis...

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Publisher copy:
10.1016/j.jacc.2005.12.057

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Journal:
Journal of the American College of Cardiology
Volume:
47
Issue:
10
Pages:
1959-1966
Publication date:
2006-05-05
DOI:
EISSN:
1558-3597
ISSN:
0735-1097
URN:
uuid:2809b611-e727-4c5c-9ed6-6a87a337aebf
Source identifiers:
223223
Local pid:
pubs:223223

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