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Journal article

White matter and lesion T1 relaxation times increase in parallel and correlate with disability in multiple sclerosis.

Abstract:

Previous studies have established the clinical relevance of hypointense lesions ("black holes") on T1-weighted MRI as a surrogate marker for pathological change [36]. In contrast to measuring the volume of "black holes", the direct measurement of T1 values allows an objective assessment of the changes contributing to hypointensity both in the focal lesions and in the normal appearing white matter (NAWM). The aims of this study were first, to determine the relationship between T1 values in the...

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Publication status:
Published

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Publisher copy:
10.1007/s00415-002-0837-7

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Journal of neurology More from this journal
Volume:
249
Issue:
9
Pages:
1279-1286
Publication date:
2002-09-01
DOI:
EISSN:
1432-1459
ISSN:
0340-5354
Language:
English
Keywords:
Pubs id:
pubs:116179
UUID:
uuid:280525ca-ea59-4f25-b6fe-67141fd8da65
Local pid:
pubs:116179
Source identifiers:
116179
Deposit date:
2012-12-19

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