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A boundary preserving numerical algorithm for the Wright-Fisher model with mutation

Abstract:

The Wright-Fisher model is an Itô stochastic differential equation that was originally introduced to model genetic drift within finite populations and has recently been used as an approximation to ion channel dynamics within cardiac and neuronal cells. While analytic solutions to this equation remain within the interval [0,1], current numerical methods are unable to preserve such boundaries in the approximation. We present a new numerical method that guarantees approximations to a form of Wri...

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Publication status:
Published

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Publisher copy:
10.1007/s10543-011-0351-3

Authors


Journal:
BIT NUMERICAL MATHEMATICS
Volume:
52
Issue:
2
Pages:
283-304
Publication date:
2012-06-01
DOI:
EISSN:
1572-9125
ISSN:
0006-3835
Source identifiers:
341697
Language:
English
Keywords:
Pubs id:
pubs:341697
UUID:
uuid:2802986b-3810-46f1-944a-5188fa22e4a6
Local pid:
pubs:341697
Deposit date:
2013-11-17

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