NMR studies of partially folded molten-globule states.
Nuclear magnetic resonance (NMR) spectroscopy is a powerful technique for the study of the structure, dynamics, and folding of proteins in solution. It is particularly powerful when applied to dynamic or flexible systems, such as partially folded molten-globule states of proteins, which are not usually amenable to X-ray crystallography. This chapter describes NMR methods suitable for the characterization of molten-globule states. These include pulsed-field-gradient NMR techniques for the meas...Expand abstract
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