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Journal article : Comment

Discoidin domain receptors: Microenvironment sensors that promote cellular migration and invasion

Abstract:

Extracellular matrix (ECM) provides cells scaffolding for cell migration and microenvironment for various cellular functions. Collagens are major ECM components in tissue and discoidin domain receptors (DDRs) are receptor tyrosine kinases (RTK) that recognise fibrillar collagens. Unlike other RTK, their ligands are solid ECM the that are abundantly present in the pericellular environment in various tissue, and thus its activation and regulations are unique amongst RTK family. It is emerging t...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1080/19336918.2018.1460011

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
Publisher:
Taylor and Francis Publisher's website
Journal:
Cell Adhesion and Migration Journal website
Volume:
12
Issue:
4
Pages:
378-385
Publication date:
2018-05-08
Acceptance date:
2018-03-26
DOI:
EISSN:
1933-6926
ISSN:
1933-6918
Source identifiers:
842281
Keywords:
Subtype:
Comment
Pubs id:
pubs:842281
UUID:
uuid:27c2ffc9-b8fc-4752-bed0-2a9d9c61f580
Local pid:
pubs:842281
Deposit date:
2018-04-19

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