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Immediate versus deferred zidovudine (AZT) in asymptomatic or mildly symptomatic HIV infected adults.

Abstract:

BACKGROUND: Zidovudine (AZT) monotherapy was the first antiretroviral drug to be tested widely. Subsequent trials in asymptomatic or early symptomatic HIV infection indicated short-term delays in disease progression with AZT, but not improved survival. OBJECTIVES: To assess the effects of immediate versus deferred zidovudine (AZT) on HIV disease progression and survival. SEARCH STRATEGY: Investigators and pharmaceutical companies were contacted, and MEDLINE searches were supplemented by sear...

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Publisher copy:
10.1002/14651858.cd002039

Authors


Darbyshire, J More by this author
Foulkes, M More by this author
Babiker, A More by this author
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Journal:
The Cochrane database of systematic reviews
Issue:
3
Pages:
CD002039
Publication date:
2000
DOI:
EISSN:
1469-493X
ISSN:
1469-493X
URN:
uuid:27aa5830-d5fa-4aea-b5be-ff0f4ad16a0f
Source identifiers:
196435
Local pid:
pubs:196435

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