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The role of cytokines in the pathogenesis of rheumatoid arthritis.

Abstract:

Recombinant DNA technology has made it possible to identify the cytokines expressed in the joints of people with active rheumatoid arthritis (RA). Because a large number of cytokines are expressed in the rheumatoid synovium and many of these cytokines may have redundant biological functions, it was necessary to study cytokine regulation to identify potential therapeutic targets. The regulation of interleukin 1, a proven inducer of bone and cartilage destruction in the rheumatoid synovium, was...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Journal:
Rheumatology (Oxford, England)
Volume:
38 Suppl 2
Issue:
SUPPL. 2
Pages:
3-7
Publication date:
1999-11-05
EISSN:
1462-0332
ISSN:
1462-0324
URN:
uuid:27a91b5d-4154-4a7c-9604-e1921a7dd481
Source identifiers:
481572
Local pid:
pubs:481572

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