Activation of subventricular zone stem cells after neuronal injury.

Journal article

The mammalian subventricular zone (SVZ) has garnered a tremendous amount of attention as a potential source of replacement cells for neuronal injury. This zone is highly neurogenic, harbours stem cells and supports long-distance migration. The general pattern of activation includes increased proliferation, neurogenesis and emigration towards the injury. Intrinsic transcription factors and environmental signalling molecules are rapidly being discovered that may facilitate the induction of thes...

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Authors: Kim, Y; Szele, F

• Publication status: Published
• Journal: Cell and tissue research
• Volume: 331
• Issue: 1
• Pages: 337-345
• Publication date: 2008-01-01
• DOI: 10.1007/s00441-007-0451-1
• EISSN: 1432-0878
• ISSN: 0302-766X
• Language: English
• Keywords: Humans; Multipotent Stem Cells; Neurons; Cerebral Ventricles; Stem Cells; Animals; Cell Proliferation; Cell Movement