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Asynchronous exponential growth in an age structured population of proliferating and quiescent cells.

Abstract:

A model of a proliferating cell population is analyzed. The model distinguishes individual cells by cell age, which corresponds to phase of the cell cycle. The model also distinguishes individual cells by proliferating or quiescent status. The model allows cells to transit between these two states at any age, that is, any phase of the cell cycle. The model also allows newly divided cells to enter quiescence at cell birth, that is, cell age 0. Sufficient conditions are established to assure th...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
Role:
Author
Journal:
Mathematical biosciences
Volume:
177-178
Pages:
73-83
Publication date:
2002-01-01
DOI:
EISSN:
1879-3134
ISSN:
0025-5564
URN:
uuid:274b6aa4-3b38-437a-b0a5-04b886f22586
Source identifiers:
21476
Local pid:
pubs:21476

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