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Journal article

Disconnection of drug-response and placebo-response in acute-phase antipsychotic drug trials on schizophrenia? Meta-regression analysis

Abstract:

Differences in efficacy between antipsychotics and placebo in schizophrenia trials have decreased over the past decades. Previous studies have tried to identify potential explanatory factors focusing on response to placebo; however, it is still not clear which factors, if any, specifically moderate drug-response, as they may be different from those moderating placebo-response. Therefore, in this meta-regression analysis we explore whether there is an interaction between drug-response and plac...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1038/s41386-019-0440-6

Authors


Chaimani, A More by this author
Mavridis, D More by this author
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Publisher:
Springer Nature Publisher's website
Journal:
Neuropsychopharmacology Journal website
Volume:
44
Issue:
11
Pages:
1955–1966
Publication date:
2019-06-18
Acceptance date:
2019-06-10
DOI:
EISSN:
1740-634X
ISSN:
0893-133X
Pubs id:
pubs:1010550
URN:
uri:2744727d-a647-493e-be46-ece0a3151493
UUID:
uuid:2744727d-a647-493e-be46-ece0a3151493
Local pid:
pubs:1010550

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