Journal article icon

Journal article

The inhibitory receptor LILRB1 modulates the differentiation and regulatory potential of human dendritic cells.

Abstract:

Dendritic cells (DCs) link innate and adaptive immunity, initiating and regulating effector cell responses. They ubiquitously express members of the LILR (ILT, LIR, CD85) family of molecules, some of which recognize self-HLA molecules, but little is known of their possible functions in DC biology. We demonstrate that the inhibitory receptor LILRB1 (ILT2, LIR1, CD85j) is selectively up-regulated during DC differentiation from monocyte precursors in culture. Continuous ligation of LILRB1 modula...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Waller, EC More by this author
Roghanian, A More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Expand authors...
Journal:
Blood
Volume:
111
Issue:
6
Pages:
3090-3096
Publication date:
2008-03-05
DOI:
EISSN:
1528-0020
ISSN:
0006-4971
URN:
uuid:273ae498-f2cc-4980-832f-fcdec8a0d5f0
Source identifiers:
141438
Local pid:
pubs:141438

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP